The mode of action of anticancer gold-based drugs: a structural perspective.
نویسندگان
چکیده
The interactions between a few representative gold-based drugs and hen egg white lysozyme were studied by X-ray crystallography. High resolution crystal structures solved for three metallodrug-protein adducts provide valuable insight into the molecular mechanism of these promising metal compounds and the inherent protein metalation processes.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 86 شماره
صفحات -
تاریخ انتشار 2013